Mechanism of Action of Flavonoids as Anti-inflammatory Agents: A Review

作者: Permender Rathee , Hema Chaudhary , Sushila Rathee , Dharmender Rathee , Vikash Kumar

DOI: 10.2174/187152809788681029

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摘要: Flavonoids are polyphenolic compounds that occur ubiquitously in plants having a variety of biological effects both vitro and vivo. They have been found to antimicrobial, antiviral, anti-ulcerogenic, cytotoxic, anti-neoplastic, mutagenic, antioxidant, antihepatotoxic, antihypertensive, hypolipidemic, antiplatelet anti-inflammatory activities. also biochemical effects, which inhibit number enzymes such as aldose reductase, xanthine oxidase, phosphodiesterase, Ca(+2)-ATPase, lipoxygenase, cycloxygenase, etc. regulatory role on different hormones like estrogens, androgens thyroid hormone. activity proliferative exudative phases inflammation. Several mechanisms action proposed explain flavonoids. The aim the present review is give an overview mechanism potential

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