Regular exercise-induced increased number and activity of circulating endothelial progenitor cells attenuates age-related decline in arterial elasticity in healthy men

作者: Zhen Yang , Wen-Hao Xia , Chen Su , Fang Wu , Yuan-Yuan Zhang

DOI: 10.1016/J.IJCARD.2011.08.055

关键词:

摘要: Abstract Background Deficiency in number and activity of circulating EPCs is associated with reduced arterial elasticity humans advancing aging. Physical exercise can increase the humans. Here we investigated whether regular exercise-induced enhanced endothelial progenitor cells (EPCs) improves age-related decline healthy men. Methods In a cross-sectional study, as well brachial-ankle pulse wave velocity (baPWV) young older sedentary or endurance-trained men were studied. Then observed effect on baPWV 10 Results both men, significantly low compared which was paralleled to increased baPWV. After three months exercise, increased, decreased. However, decreased higher. There close correlation between Multivariate analysis identified proliferative an independent predictor Conclusions The present study demonstrates for first time that physical attenuates These findings provide novel insights into protective effects vascular injury.

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