作者: Aubry Kern Miller , Jacob Berger , Saul Jaime-Figueroa , Shu-Hai Zhao , Klaus Kurt Weinhardt
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摘要: The present invention is directed to pyrimidine derivatives, and pharmaceutically acceptable salts N-oxides thereof, which exhibit useful pharmacological properties, in particular use as selective 5HT2B-antagonists, their preparation, pharmaceutical compositions comprising them the treatment of various diseases, especially migraine. also formulations methods for treatment.