Characterization of neoplastic mononuclear cells on tissue sections.

摘要: Immunological advances have elucidated that among lymphoreticular cells — especially lymphocytes a much greater heterogeneity exists than previously thought. With regard to malignant lymphomas we may, thus, expect compared purely morphological criteria an immunological identification of permits us gain better understanding the origin neoplastic cell, and, consequently, elaborate classification lymphomas. An established technique identify mononuclear subpopulations in tissue infiltrates consists liberating by mechanical disaggregation and enzymatic treatment, followed typing using surface markers (11).