The serological response of the common seal (Phoca vitulina) and the grey seal (Halichoerus grypus) to phocine distemper virus as measured by a canine distemper virus neutralisation test

摘要: The application of a canine distemper virus (CDV) neutralisation test revealed that antibody titres up to 11,620 were present in the sera common seals during epizootic phocine British waters. However, later stages and afterwards, surprisingly high proportion animals still seronegative. Titres from 90 183 diseased probably indicative partial immunosuppression. A few with proven had less than 64, this being evidence more profound Recovered tended have moderate some cases these persisted for at least 6.5 months. By contrast, administration an inactivated CDV vaccine produced which declined rapidly very low levels within same period. Infection also occurred grey 1988 but without severe mortality. Antibody species nearly always lay range 128-734 or around level 12 In both seals, was transferred by suckling mother pup absorption seemed take place slowly domestic mammals.