作者: Karol S. Bruzik
DOI: 10.1002/9780470048672.WECB447
关键词:
摘要: Phosphatidylinositol phosphates are cellular signaling molecules that came to prominence in the mid-1980s, after inositol trisphosphate was discovered as a key intracellular second messenger generated from phosphatidylinositol 4,5-bisphosphate response stimulation of wide range extra-cellular receptors. Since then, many novel and phospholipids have been discovered, their functions studied. The roles these encompass regulation processes indispensable organism homeostasis. On level, include cell growth differentiation, motility invasiveness, vesicular trafficking, protein targeting specific compartments. This review focuses on biosynthesis biological phospholipids.