Use of Drug Discrimination Learning in Behavioral Toxicology: Classification and Characterization of Toxins

摘要: Publisher Summary This chapter focuses on drug discrimination learning, a research design used exclusively in behavioral pharmacology. Within pharmacology, this general is primarily the assessment of stimulus properties recreational and abused drugs. The also extensively characterization. Once discriminative control established to particular drug, other compounds can be co-administered with training determine if what extent these either antagonize or potentiate drug. interactions by procedure has focused antagonism, however, assessments potentiation have been made. It noted that noradrenergic antagonist yohimbine potentiated effects amphetamine, thought mediated antagonistic at α2 presynaptic autoreceptors. Given amphetamine may noradrenergically mediated, antagonism autoreceptors should increase overall activity its effects. discusses application learning classification elaborates pharmacology toxicology.