Delayed-type hypersensitivity to myelin basic proteins in mice susceptible to allergic encephalomyelitis.

作者: D. Scott Linthicum , George A. Hashim

DOI: 10.1007/BF00964673

关键词:

摘要: The delayed-type hypersensitivity (DTH) response in mice immunized with autologous spinal cord homogenate or purified myelin basic protein (MBP) was measured by the125I-UdR uptake ear assay. Mice were tested for DTH responses MBP preparations from different species and synthetic peptides. 114–122 68–84 peptide regions appear to be major determinants inducing eliciting the which are susceptible allergic encephalomyelitis.

参考文章(30)
Håkan Bergstrand, Immunochemistry of Encephalitogenic Protein Immunochemistry of Proteins. pp. 315- 370 ,(1977) , 10.1007/978-1-4613-4190-1_5
R B Fritz, C H Chou, D E McFarlin, C B Pettinelli, Encephalitogenic activity of guinea pig myelin basic protein in the SJL mouse. Journal of Immunology. ,vol. 129, pp. 1209- 1211 ,(1982)
George A. Hashim, Richard D. Sharpe, Evelyn F. Carvalho, Definition and Synthesis of the Essential Amino Acid Sequence for Experimental Allergic Encephalomyelitis in Lewis Rats Journal of Immunology. ,vol. 121, pp. 665- 670 ,(1978)
R B Fritz, C H Chou, D E McFarlin, Relapsing murine experimental allergic encephalomyelitis induced by myelin basic protein. Journal of Immunology. ,vol. 130, pp. 1024- 1026 ,(1983)
Raymond Shapira, Sarah S. McKneally, Frank Chou, Robert F. Kibler, Encephalitogenic Fragment of Myelin Basic Protein AMINO ACID SEQUENCE OF BOVINE, RABBIT, GUINEA PIG, MONKEY, AND HUMAN FRAGMENTS Journal of Biological Chemistry. ,vol. 246, pp. 4630- 4640 ,(1971) , 10.1016/S0021-9258(18)62056-3
R Shapira, R B Fritz, C H Chou, Encephalitogenic activity of the small form of mouse myelin basic protein in the SJL/J mouse. Journal of Immunology. ,vol. 130, pp. 2183- 2186 ,(1983)
Patrick R. Carnegie, Claude C. A. Bernard, Experimental Autoimmune Encephalomyelitis in Mice: Immunologic Response to Mouse Spinal Cord and Myelin Basic Proteins Journal of Immunology. ,vol. 114, pp. 1537- 1540 ,(1975)
Seymour Levine, Richard Sowinski, Experimental allergic encephalomyelitis in congenic strains of mice Immunogenetics. ,vol. 1, pp. 352- 356 ,(1974) , 10.1007/BF01564073
Lynn E. Spitler, Christine M. von Muller, H. Hugh Fudenberg, Edwin H. Eylar, EXPERIMENTAL ALLERGIC ENCEPHALITIS : DISSOCIATION OF CELLULAR IMMUNITY TO BRAIN PROTEIN AND DISEASE PRODUCTION Journal of Experimental Medicine. ,vol. 136, pp. 156- 174 ,(1972) , 10.1084/JEM.136.1.156