The IgG antibody profile to various antigen regions of hepatitis C virus differs in oral fluid and serum of patients with chronic hepatitis C

摘要: Maticic M, Poljak Seme K, Skaleric U. The IgG antibody profile to various antigen regions of hepatitis C virus differs in oral fluid and serum patients with chronic C. Oral Microbiol Immunol 2003: 18: 176–182. © Blackwell Munksgaard, 2003. Antibodies (HCV) can be detected not only but also fluid. aim the study was determine reactivity directed six HCV evaluate significance pattern compared serum. samples 32 viremic were collected detect antibodies incorporated as bands into modified commercial updated third generation line immuno-assay. Compared serum, a significantly lower cumulative response five antigens found highest prevalence recorded C1 (78%), whereas most frequent NS3 (100%). absence E2 similar both body fluids. discrepancy between indicates possible existence local viral replication, mutants, inhibitors cavity and, probably, leakage muco-vascular barrier.