Active cytomegalovirus infection in human periodontitis.
作者： A. Contreras , J. Slots
DOI: 10.1111/J.1399-302X.1998.TB00700.X
关键词: Periodontitis 、 Herpesviridae 、 Betaherpesvirinae 、 Virus 、 Biology 、 Polymerase chain reaction 、 Virology 、 Gingival and periodontal pocket 、 Human cytomegalovirus 、 Reverse transcription polymerase chain reaction 、 Immunology
摘要: This study used the reverse transcription polymerase chain reaction method to determine mRNA of subgingival human cytomegalovirus (HCMV) in six adult and three localized juvenile periodontitis patients. The oligonucleotide primers targeted major capsid protein gene active HCMV infection. transcript was detected deep periodontal pockets two patients but not any shallow sites. findings suggest that replication can occur Further studies are necessary establish whether reactivation correlates with initiation or progression destructive disease.
sci-hub.se 参考文章(60)
JP Maciejewski, EE Bruening, RE Donahue, ES Mocarski, NS Young, SC St Jeor, Infection of hematopoietic progenitor cells by human cytomegalovirus. Blood. ,vol. 80, pp. 170- 178 ,(1992) , 10.1182/BLOOD.V80.1.170.BLOODJOURNAL801170
P Reusser, LD Fisher, CD Buckner, ED Thomas, JD Meyers, Cytomegalovirus infection after autologous bone marrow transplantation: occurrence of cytomegalovirus disease and effect on engraftment Blood. ,vol. 75, pp. 1888- 1894 ,(1990) , 10.1182/BLOOD.V75.9.1888.1888
R M Stenberg, D R Thomsen, M F Stinski, Structural analysis of the major immediate early gene of human cytomegalovirus. Journal of Virology. ,vol. 49, pp. 190- 199 ,(1984) , 10.1128/JVI.49.1.190-199.1984
S A Spector, R Merrill, D Wolf, W M Dankner, Detection of human cytomegalovirus in plasma of AIDS patients during acute visceral disease by DNA amplification. Journal of Clinical Microbiology. ,vol. 30, pp. 2359- 2365 ,(1992) , 10.1128/JCM.30.9.2359-2365.1992
J Gozlan, J M Salord, C Chouaïd, C Duvivier, O Picard, M C Meyohas, J C Petit, Human cytomegalovirus (HCMV) late-mRNA detection in peripheral blood of AIDS patients: diagnostic value for HCMV disease compared with those of viral culture and HCMV DNA detection. Journal of Clinical Microbiology. ,vol. 31, pp. 1943- 1945 ,(1993) , 10.1128/JCM.31.7.1943-1945.1993
P. Dal Monte, T. Lazzarotto, A. Ripalti, M.P. Landini, Human cytomegalovirus infection: a complex diagnostic problem in which molecular biology has induced a rapid evolution. Intervirology. ,vol. 39, pp. 193- 203 ,(1996) , 10.1159/000150495
E S Mocarski, M F Stinski, Persistence of the cytomegalovirus genome in human cells. Journal of Virology. ,vol. 31, pp. 761- 775 ,(1979) , 10.1128/JVI.31.3.761-775.1979
M Chee, S A Rudolph, B Plachter, B Barrell, G Jahn, Identification of the major capsid protein gene of human cytomegalovirus. Journal of Virology. ,vol. 63, pp. 1345- 1353 ,(1989) , 10.1128/JVI.63.3.1345-1353.1989
P Stashenko, W J Peros, R L Kent, F E Dewhirst, J M Ago, Synergistic interactions between interleukin 1, tumor necrosis factor, and lymphotoxin in bone resorption. Journal of Immunology. ,vol. 138, pp. 1464- 1468 ,(1987)
Bodo Plachter, Christian Sinzger, Gerhard Jahn, Cell types involved in replication and distribution of human cytomegalovirus Advances in Virus Research. ,vol. 46, pp. 195- 261 ,(1996) , 10.1016/S0065-3527(08)60073-1