作者: Mehmet Yapar , Işıl Saygun , Atilla Özdemir , Ayhan Kubar , Sermet Şahin
DOI: 10.1902/JOP.2003.74.11.1634
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摘要: Background: Recent studies have demonstrated that various human viruses, especially cytomegalovirus (HCMV) and Epstein-Barr virus type-1 (EBV-1), seem to play a part in the pathogenesis of periodontitis. The aim this investigation was evaluate subgingival presence HCMV EBV patients with aggressive periodontitis (AgP) healthy subjects examine effect treatment on incidence these viruses months following surgery. Methods: A polymerase chain reaction (PCR) method determined EBV-1. Subgingival plaque samples from 17 consecutive AgP 16 controls were collected. indices measured: index (PI), gingival (GI), probing depths (PD), clinical attachment loss (CAL). Clinical parameters assessed pretherapy at 3 surgical antimicrobial therapy. Results: detected 64.7% but not (P <0.001) EBV-1 70.6% Ag...