The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation
作者： Ryan Schmidt , Kathrin Plath
DOI: 10.1186/GB-2012-13-10-251
关键词:
摘要: Somatic cell reprogramming to induced pluripotent stem (iPS) cells by defined factors is a form of engineered reverse development carried out in vitro. Recent investigation has begun elucidate the molecular mechanisms whereby these function reset epigenome.
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