Interleukin-3, Interleukin-5, and Cancer
作者： Arseniy E. Yuzhalin , Anton G. Kutikhin
DOI: 10.1016/B978-0-12-801121-8.00004-X
关键词:
摘要: Interleukin (IL)-3 and IL-5 are both regarded as hematopoietic cytokines, which means they provide positive negative regulation of differentiation, maturation, survival, proliferation, commitment, functional activation progenitor cells. This chapter briefly summarizes the existing knowledge on impact these cytokines malignancies. The will begin by giving definition family cytokines. following section points out molecular mechanisms that underlie link between activity interleukins features tumor development. Third, we shall discuss results preclinical studies role IL-3 cancer progression. Furthermore, evaluating prognostic considered well. Finally, shed light IL-3R its use a targeted therapy drug for
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