Inhibition of Thiopurine S-methyltransferase Activity by Impurities in Commercially Available Substrates: A Factor for Differing Results of TPMT Measurements
作者： T. Kröplin , C. Fischer , H. Iven
关键词:
摘要: Objectives: Thiopurine S-methyltransferase (TPMT) activity, when measured in red blood cells (RBC) with a recently published TPMT activity assay using 6‐thioguanine (6-TG) as substrate, could not be reproduced another laboratory. We investigated factors which influence the results of measurement.
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