Hepatitis C virus (HCV) infection & risk factors for HCV positivity in injecting & non-injecting drug users attending a de-addiction centre in northern India.

作者: Debasish Basu , ArunKumar Sharma , Sunil Gupta , Naresh Nebhinani , Vineet Kumar

DOI: 10.4103/0971-5916.166596

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摘要: Background & objectives: Injecting drug use is a major route of hepatitis C virus (HCV) infection in India, but there may be other risk factors also. This study was carried out to determine the seroprevalence anti-HCV antibody injecting users (IDUs) vs. non-IDUs (NIDUs), and estimates for HCV seropositivity total sample substance with regard various demographic, clinical, behavioural personality factors. Methods: The IDUs (n = 201) NIDUs 219) were assessed clinical information, rated on instruments severity dependence, behaviour profiles. Anti-HCV tested by ELISA confirmed recombinant immunoblot assay (RIBA) test. Results: Almost one-third (64 201; 31.8%) positive antibody, as opposed only seven (3.2%) NIDUs. four strongly associated positivity multivariate analysis sharing syringe [Exp(B) 75.04; 95%CI 18.28-307.96; P Interpretation conclusions: Our showed high IDUs. In users, significantly independently several behavioural,

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