Expression of heme oxygenase isoenzymes 1 and 2 in normal and asthmatic airways: effect of inhaled corticosteroids.

作者: SAM LIM , DAVID GRONEBERG , AXEL FISCHER , TIMOTHY OATES , GAETANO CARAMORI

DOI: 10.1164/AJRCCM.162.5.9909081

关键词:

摘要: … to be an antioxidant enzyme that catabolizes heme to … demonstrate low to normal values of CO in exhaled air (18, 19), … warm to room temperature and fixed in acetone at 4 C for 10 min, …

参考文章(36)
P. A. Dennery, H. E. Wong, K. J. Sridhar, P. A. Rodgers, J. E. Sim, D. R. Spitz, Differences in basal and hyperoxia-associated HO expression in oxidant-resistant hamster fibroblasts American Journal of Physiology-lung Cellular and Molecular Physiology. ,vol. 271, ,(1996) , 10.1152/AJPLUNG.1996.271.4.L672
Vuokko L Kinnula, Kari O Raivio, J D Crapo, Generation and disposal of reactive oxygen metabolites in the lung Laboratory Investigation. ,vol. 73, pp. 3- 19 ,(1995)
B.A. Freeman, J.D. Crapo, Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria. Journal of Biological Chemistry. ,vol. 256, pp. 10986- 10992 ,(1981) , 10.1016/S0021-9258(19)68544-3
Z Allakhverdi, O Ghaffar, Q Hamid, P M Renzi, A D Luster, E A Garcia-Zepada, M D Rothenberg, S Abi-Younes, B Lamkhioued, Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation. Journal of Immunology. ,vol. 159, pp. 4593- 4601 ,(1997)
Phyllis A Dennery, Pamela A Rodgers, Melissa A Lum, Blair C Jennings, Vida Shokoohi, Hyperoxic Regulation of Lung Heme Oxygenase in Neonatal Rats Pediatric Research. ,vol. 40, pp. 815- 821 ,(1996) , 10.1203/00006450-199612000-00007
Yan Lavrovsky, George S. Drummond, Nader G. Abraham, Downregulation of the human heme oxygenase gene by glucocorticoids and identification of 56b regulatory elements. Biochemical and Biophysical Research Communications. ,vol. 218, pp. 759- 765 ,(1996) , 10.1006/BBRC.1996.0135
P J Lee, J Alam, S L Sylvester, N Inamdar, L Otterbein, A M Choi, Regulation of Heme Oxygenase-1 Expression in Vivo and in Vitro in Hyperoxic Lung Injury American Journal of Respiratory Cell and Molecular Biology. ,vol. 14, pp. 556- 568 ,(1996) , 10.1165/AJRCMB.14.6.8652184
G. F. Vile, S. Basu-Modak, C. Waltner, R. M. Tyrrell, Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 2607- 2610 ,(1994) , 10.1073/PNAS.91.7.2607