Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in urban health facilities in Yaoundé, central province, Cameroon

摘要: After adoption of artesunate-amodiaquine (AS/AQ) as first-line therapy for the treatment uncomplicated malaria by control programme, this study was designed to assess availability anti-malarial drugs, practices and acceptability new protocol health professionals, in urban facilities drugstores Yaounde city, Cameroon. Between April August 2005, retrospective current information collected consulting registers interviewing practitioners using a structured questionnaire. In twenty-seven trade-named drugs have been identified drugstores; quinine tablets (300 mg) were most affordable drugs. Chloroquine restricted food market places no generic artemisinin derivative available public centres. facilities, 13.6% professionals informed about guidelines; 73.5% supported use AS-AQ therapy. However, 38.6% apprehended its due adverse events attributed amodiaquine. Malaria mainly based on diagnosis fever. Quinine mg tablets) commonly prescribed drug adults (44.5%) pregnant women (52.5%). Artequin® cited artemsinin-based combination (ACT) (9.9%). Medical sales representatives main sources anti-malarials. The AS/AQ not implemented 2005 Yaounde, despite wide range anti-malarials derivatives available. Nevertheless, medical will support combination, when it is paediatric formulation, at an price. Training, participation decision-making one key elements improve adherence guidelines. This baseline be useful monitor progress ACT implementation