摘要: Although RNA bacteriophages were discovered only relatively recently (Loeb and Zinder, 1961), they have attracted considerable attention ever since. Because of their small size, one could hope that these would be the first viruses whose complete structure elucidated, for which all biological events constituting infection cycle understood in molecular biophysical detail. These include phage adsorption penetration, expression viral genetic information, interference with host cell metabolism, replication genome, assembly, virus release through lysis. aims certainly not yet been completely fulfilled, today biology is undoubtedly most advanced any living organism (assuming course a considered an “organism,” question definition). Another reason interest phages constitute convenient model system may contribute considerably to understanding general. The versatility microbial biochemical experimentation, combined short (less than 30 min) high yields (more 2 × 1012 pfu/ml),* offer obvious practical advantages.
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