Anti-infectives : recent advances in chemistry and structure-activity relationships

摘要: Part 1 Advances in antibacterials/antibiotics: the glycopeptide story - how to kill deadly "superbugs", D.H. Williams et al design and synthesis of novel oxazolidinones active against multidrug-resistant bacteria, M.R. Barbachyn from Michael reaction clinic, J.C. Barriere J.M. Paris salinomycin, R.C.D. Brown P. Kocienski inhibition protein export bacteria signalling a new role for beta-lactams, A.E. Allsop synthetic studies toward complex polyether macrolides marine origin, S.D. Burke trinems antibacterial activity generation S. Biondi concepts penicillin sensitive enzymes, Pfleiger design, antibacterial, antifungal antiviral agents, M.J. Miller al. 2 antifungals: chemistry azole antifungals fluconazole beyond, S.D.A. Street tubulins target D.W. Hollomon cell-wall emerging targets, N.H. Georgopapadakou strobilurin analogues as inhibitors mitochondrial respiration fungi, Clough advances broad-spectrum orally recent leading discovery SCH56592, A.K. Saksena 3 antivirals: 4'-thio-2'-deoxyribonucleosides, their biological properties review, R.T. Walker invention development CRIXIVAN(R) an HIV protease inhibitor, B.D. Dorsey evaluation some nucleotides HIV, C. McGuigan overview TSAO-T derivatives, "peculiar" class HIV-1 specific RT inhibitors, M.-J. Camarasa sialidase treatment influenza, P.W. Smith viral proteinases targets viruses other than HIV-1, J.S. Mills testing cysteine proteinases, Frormann nucleosides with six-membered carbohydrate moiety structural requirements activity, Herdewijn.