Engineering the niche for stem cells.
作者： Shawna Tan , Nicholas Barker
DOI: 10.3109/08977194.2013.859683
关键词:
摘要: AbstractMuch has been made about the potential for stem cells in regenerative medicine but reality is that development of actual therapies slow. Adult rely heavily on assortment biochemical and biophysical elements constitute local microenvironment which they exist. One goal biomedicine to create an artificial yet biofunctional niche support multipotency, differentiation proliferation. Such tools would facilitate more conclusive experimentation by biologists, pharmaceutical scientists tissue engineers. While many bioengineering techniques platforms are already use, technological innovations now allow this be done at a higher resolution specificity. Ultimately, multidisciplinary integration engineering biology will generated scale can clinically exploited. Using systems intestinal, hematopoietic epidermal tissues, article summarizes various approac...
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