摘要: Publisher Summary This chapter discusses the significance of sex chromatin. Several morphological aspects chromatin are interest, especially when one bears in mind that this chromocenter is a single X chromosome condensed or positively heteropycnotic state. The following account refers to cells females. In males, occasional nuclei contain particles mimic chromatin, but there no regularity pattern and chromocenters question probably represent regions autosomes. focuses on possible genetic heteropycnosis two chromosomes somatic It seems reasonable synthesis release messenger RNA would be suppressed region tightly coiled compact. While per se significant as useful cytological marker tests used clinical diagnostic aids, its true biological sense lies derivation. staining properties human tissues other animals, derivation
sci-hub.se 参考文章(231)
Hermann A. Hienz, [Morphological determination of sex based on the cell nucleus in mammals & in man]. Deutsche Medizinische Wochenschrift. ,vol. 82, pp. 1986- 1991 ,(1957) , 10.1055/S-0028-1117031
Avery A. Sandberg, George F. Koepf, Theodore S. Hauschka, John E. Hasson, Milton N. Goldstein, An XYY man with progeny indicating familial tendency to non-disjunction. American Journal of Human Genetics. ,vol. 14, pp. 22- 30 ,(1962)
Nirmala Kesaree, Paul V. Woolley, Michael Samson, A phenotypic female with 49 chromosomes, presumably XXXXX The Journal of Pediatrics. ,vol. 63, pp. 1099- 1103 ,(1963) , 10.1016/S0022-3476(63)80190-0
Murray L. Barr, Hugh A. Lindsay, Further observations on the behaviour of nuclear structures during depletion and restoration of Nissl material Journal of Anatomy. ,vol. 89, pp. 47- 62 ,(1955)
William M. Davidson, D. Robertson Smith, Symposium on nuclear sex Heinemann. ,(1958)
Mary F. Lyon, Sex chromatin and gene action in the mammalian X-chromosome. American Journal of Human Genetics. ,vol. 14, pp. 135- 148 ,(1962)
Murray L. Barr, David H. Carr, Earl R. Plunkett, An XXXX sex chromosome complex in two mentally defective females. Canadian Medical Association Journal. ,vol. 84, pp. 131- 137 ,(1961)
P JACOBS, Cytogenetic studies in primary amenorrhoea. The Lancet. ,vol. 277, pp. 1183- 1189 ,(1961) , 10.1016/S0140-6736(61)91939-0
M. L. Barr, H. C. Soltan, D. H. Carr, E. R. Plunkett, Ruth G. Wiens, THE XXYY VARIANT OF KLINEFELTER'S SYNDROME. Canadian Medical Association Journal. ,vol. 90, pp. 575- 580 ,(1964)
Arthur R. Sohval, Joseph A. Gaines, J.Lester Gabrilove, Clinical experiences with the skin biopsy method of detecting chromosomal sex. American Journal of Obstetrics and Gynecology. ,vol. 70, pp. 1074- 1082 ,(1955) , 10.1016/0002-9378(55)90016-8