18Fluorodeoxyglucose Positron Emission Tomography in the Diagnosis and Staging of Lung Cancer: A Systematic Review

摘要: Lung cancer is the leading cause of cancer-related death in industrialized countries. The overall mortality rate for lung high, and early diagnosis provides best chance survival. Diagnostic tests guide management decisions, clinicians increasingly use diagnostic imaging an effort to improve patients with cancer. This systematic review, expansion a health technology assessment conducted 2001 by Institute Clinical Evaluative Sciences, evaluates accuracy utility 18fluorodeoxyglucose positron emission tomography (PET) staging Through search literature, we identified relevant assessments, randomized trials, meta-analyses published since earlier including 12 evidence summary reports 15 prospective studies PET. PET appears have high sensitivity reasonable specificity differentiating benign from malignant lesions as small 1 cm. superior computed mediastinal non-small cell (NSCLC). Randomized trials evaluating potentially resectable NSCLC report conflicting results terms relative reduction number noncurative thoracotomies. has not been studied extensively small-cell cancer, but available data show that it good extensive- versus limited-stage disease. Although current conflicting, may early-stage identifying who metastatic disease beyond scope surgical resection evident standard preoperative procedures. Further are necessary establish clinical part