Pre-induction cervical ripening with 25 μg and 50 μg vaginal misoprostol in 181 nulliparous parturients

摘要: Objective. To evaluate the effect of intravaginally misoprostol at start dosages 25 μg and 50 when used for pre-induction cervical ripening among nulliparous parturients.Methods. Our observational study involves all cases partus induction consecutively registered in a Norwegian hospital between September 2002 August 2006, with following inclusion criteriae: nulliparous, singleton pregnancies ≥37 weeks, an unfavourable cervix (Bishop score ≤6), viable fetus >2499 g, received vaginally every 6 h upto four times. Seventy-six women started (25 μg-group) 105 (50 μg-group). All continued μg. Primary outcome was vaginal delivery within 48 after first dose. Secondary caesarean section performed 96.Results. Vaginal initial dose occurred more often μg-group than (75 vs. 58%, p = 0.018). The rate lower ...