A randomized prospective study of misoprostol and dinoproston for induction of labor
作者： PATRICK BELFRAGE , ELI SMEDVIG , LEIF GJESSING , TORBJØRN MOE EGGEBØ , INGER ØKLAND
DOI: 10.1034/J.1600-0412.2000.0790121065.X
关键词: Misoprostol 、 Cervix 、 Prostaglandin 、 Medicine 、 Randomized controlled trial 、 Randomization 、 Obstetrics 、 Labor induction 、 Pregnancy 、 Uterus
摘要: Background. Misoprostol, a prostaglandin E1 analog registered for the prevention of gastric ulcers in NSAID-drug users, has been reported to be more effective labor induction than standard prostaglandin, dinoproston after vaginal application. There have some concerns about possible hyperstimulation uterine activity and safety fetus with this new drug.Methods. Two hundred ten patients, 36 weeks pregnant or more, an unfavorable cervix, single pregnancy, intact membranes were randomized receive misoprostol, 50 micrograms intravaginally every 6 hours, 0.5 mg intracervically 12 hours maximum 24 induction.Results. Time from delivery was shorter both primigravidae multigravidae application misoprostol failed common misoprostol. no differences condition newborns two groups, accordin...
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