Regulation of Cytokines and Chemokines in Human Mycobacterium tuberculosis Infection

作者: Zahra Toossi , Jerrold J. Ellner

DOI: 10.1007/978-1-59259-309-5_10

关键词:

摘要: Tuberculosis (TB) continues to scourge mankind with a mortality of approx 3 million and an incidence 10 new cases each year (1). One-third the world population is infected Mycobacterium tuberculosis (MTB), which signifies both success this intracellular pathogen in establishment infection humans lack effective available means prevention infection. A complete understanding interface MTB human immune response critical development immunotherapies vaccines fight against TB.

参考文章(71)
T Fleisher, S M Holland, D B Kuhns, M L Turner, E M Eisenstein, W Strober, TREATMENT OF REFRACTORY DISSEMINATED NONTUBERCULOUS MYCOBACTERIAL INFECTION WITH INTERFERON GAMMA NEW ENGLAND JOURNAL OF MEDICINE (NEJM). ,vol. 330, pp. 1348- 1355 ,(1994)
Matthias Goebeler, Karin Kilian, Reinhard Gillitzer, Manfred Kunz, Teizo Yoshimura, Eva-B. Bröcker, Ulf R. Rapp, Stephan Ludwig, The MKK6/p38 Stress Kinase Cascade Is Critical for Tumor Necrosis Factor-α–Induced Expression of Monocyte-Chemoattractant Protein-1 in Endothelial Cells Blood. ,vol. 93, pp. 857- 865 ,(1999) , 10.1182/BLOOD.V93.3.857.403K03_857_865
Carl F. Nathan, Gilla Kaplan, William R. Levis, Ali Nusrat, Margit D. Witmer, Stephen A. Sherwin, C.K. Job, Carol R. Horowitz, Ralph M. Steinman, Zanvil A. Cohn, Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy The New England Journal of Medicine. ,vol. 315, pp. 6- 15 ,(1986) , 10.1056/NEJM198607033150102
Zahra Toossi, M. Mincek, C. S. Hirsch, B. D. Hamilton, E. Seeholtzer, S. A. Fulton, Modulation of IL-12 by transforming growth factor-beta (TGF-beta) in Mycobacterium tuberculosis-infected mononuclear phagocytes and in patients with active tuberculosis. Journal of clinical & laboratory immunology. ,vol. 49, pp. 59- 75 ,(1997)
Corral L, Saha R, Willcox P, Johnson Bj, Pati Bp, Lorgat F, Lukey P, Stead P, Laochumroonvorapong P, Ress, Clinical and immune responses of tuberculosis patients treated with low-dose IL-2 and multidrug therapy. Cytokines and molecular therapy. ,vol. 1, pp. 185- 196 ,(1995)
Zahra Toossi, Cytokine circuits in tuberculosis Infectious agents and disease. ,vol. 5, pp. 98- 107 ,(1996)
Sherwood L. Gorbach, Neil R. Blacklow, John G. Bartlett, Infectious Diseases ,(1992)
J S Pober, B J Rollins, T Yoshimura, E J Leonard, Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE. American Journal of Pathology. ,vol. 136, pp. 1229- 1233 ,(1990)