The comings and goings of actin: coupling protrusion and retraction in cell motility.

作者: J Victor Small , Guenter P Resch

DOI: 10.1016/J.CEB.2005.08.004

关键词:

摘要: Cells utilize actin filaments to produce protrusive and contractile arrays that cooperate drive cell motility. The generation of the two coupling between them result from unique properties lamellipodium, a leaflet cytoplasm at edge. From lamellipodium into lamella behind, there is transition fast retrograde flow polymer driven by polymerization slow interaction anti-parallel with myosin. In addition driving protrusion, appears play role in supplying for assembly network required traction.

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