Increased circulating procoagulant and anticoagulant factors as TF and TFPI according to severity or infecting serotypes in human dengue infection
作者： Elzinandes Leal de Azeredo , Victor Edgar Fiestas Solórzano , Débora Batista de Oliveira , Cintia Ferreira Marinho , Luiz José de Souza
DOI: 10.1016/J.MICINF.2016.08.005
关键词:
摘要: Tissue Factor (TF) is the initiator of coagulation and Inhibitor (TFPI) physiological inhibitor TF/FVIIa complex. Circulating levels TF TFPI were quantified in dengue patients relationships with disease severity infecting serotype analysed. A significant decrease TPFI plasma was observed mild DF compared severe dengue. Furthermore, both factors associated haemorrhagic manifestations. Finally, significantly increased DENV-1/2 infected as DENV-4. These findings suggest that activation TF-pathway an important component DENV -related disorders.
fiocruz.br参考文章(24)
Anon Srikiatkhachorn, Sharone Green, Markers of dengue disease severity. Current Topics in Microbiology and Immunology. ,vol. 338, pp. 67- 82 ,(2010) , 10.1007/978-3-642-02215-9_6
Panya Seksarn, Sureeporn Pongsewalak, Usa Thisyakorn, Jeanne Lusher, Darintr Sosothikul, Activation of endothelial cells, coagulation and fibrinolysis in children with Dengue virus infection Thrombosis and Haemostasis. ,vol. 97, pp. 627- 634 ,(2007) , 10.1160/TH06-02-0094
Bridget A Wills, Emmanuelle E Oragui, Alick C Stephens, Olufunmilayo A Daramola, Nguyen Minh Dung, Ha Thi Loan, Nguyen Vinh Chau, Mary Chambers, Kasia Stepniewska, Jeremy J Farrar, Michael Levin, None, Coagulation Abnormalities in Dengue Hemorrhagic Fever: Serial Investigations in 167 Vietnamese Children with Dengue Shock Syndrome Clinical Infectious Diseases. ,vol. 35, pp. 277- 285 ,(2002) , 10.1086/341410
Gleicy Amorim Macedo, Josélio Maria Galvão de Araújo, Hermann Gonçalves Schatzmayr, Filipe Anibal Carvalho Costa, Ana Maria Bispo de Filippis, Flávia Barreto dos Santos, Rita Maria Ribeiro Nogueira, Virological surveillance for early warning of dengue epidemics in the State of Rio de Janeiro, Brazil Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 107, pp. 141- 146 ,(2013) , 10.1093/TRSTMH/TRS091
Rachel Tilley, Nigel Mackman, Tissue factor in hemostasis and thrombosis. Seminars in Thrombosis and Hemostasis. ,vol. 32, pp. 5- 10 ,(2006) , 10.1055/S-2006-933335
A. Phillip Owens, Nigel Mackman, Tissue factor and thrombosis: The clot starts here. Thrombosis and Haemostasis. ,vol. 104, pp. 432- 439 ,(2010) , 10.1160/TH09-11-0771
Florian Langer, Brigitte Spath, Katja Haubold, Katharina Holstein, Guy Marx, Jan Wierecky, Tim H. Brümmendorf, Judith Dierlamm, Carsten Bokemeyer, Barbara Eifrig, Tissue Factor Procoagulant Activity of Plasma Microparticles in Patients With Cancer-Associated Disseminated Intravascular Coagulation Annals of Hematology. ,vol. 87, pp. 451- 457 ,(2008) , 10.1007/S00277-008-0446-3
Elzinandes Leal de Azeredo, Robson Q. Monteiro, Luzia Maria de-Oliveira Pinto, Thrombocytopenia in Dengue: Interrelationship between Virus and the Imbalance between Coagulation and Fibrinolysis and Inflammatory Mediators Mediators of Inflammation. ,vol. 2015, pp. 313842- 313842 ,(2015) , 10.1155/2015/313842
Raj Kasthuri, Sam Glover, Jeremiah Boles, Nigel Mackman, Tissue factor and tissue factor pathway inhibitor as key regulators of global hemostasis: measurement of their levels in coagulation assays. Seminars in Thrombosis and Hemostasis. ,vol. 36, pp. 764- 771 ,(2010) , 10.1055/S-0030-1265293
Nguyen Tien Huy, Tran Van Giang, Dinh Ha Duy Thuy, Mihoko Kikuchi, Tran Tinh Hien, Javier Zamora, Kenji Hirayama, None, Factors Associated with Dengue Shock Syndrome: A Systematic Review and Meta-Analysis PLoS Neglected Tropical Diseases. ,vol. 7, pp. e2412- ,(2013) , 10.1371/JOURNAL.PNTD.0002412