Understanding the effects of mature adipocytes and endothelial cells on fatty acid metabolism and vascular tone in physiological fatty tissue for vascularized adipose tissue engineering
作者： Birgit Huber , Ann-Cathrin Volz , Petra J. Kluger
DOI: 10.1007/S00441-015-2274-9
关键词:
摘要: Engineering of large vascularized adipose tissue constructs is still a challenge for the treatment extensive high-graded burns or replacement after tumor removal. Communication between mature adipocytes and endothelial cells important homeostasis maintenance mass but, to date, mainly neglected in engineering strategies. Thus, new co-culture strategies are needed integrate successfully into functional construct. This review focuses on cross-talk considers their influence fatty acid metabolism vascular tone. In addition, properties challenges with regard these two cell types highlighted.
springer.com
core.ac.uk 
sci-hub.se 参考文章(123)
Jiri Šmahel, Adipose tissue in plastic surgery. Annals of Plastic Surgery. ,vol. 16, pp. 444- 453 ,(1986) , 10.1097/00000637-198605000-00012
A. S. Greenberg, C. Londos, J. J. Egan, Min-Kun Chang, Control of endogenous phosphorylation of the major cAMP-dependent protein kinase substrate in adipocytes by insulin and beta-adrenergic stimulation. Journal of Biological Chemistry. ,vol. 265, pp. 18769- 18775 ,(1990) , 10.1016/S0021-9258(17)30578-1
David Jablons, Andrew S. Greenberg, Richard P. Nordan, Robert O. Scow, Juan Carlos Calvo, Joseph McIntosh, Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes : a possible role for interleukin 6 in cancer cachexia Cancer Research. ,vol. 52, pp. 4113- 4116 ,(1992)
Martin Rodbell, The Metabolism of Isolated Fat Cells IV. REGULATION OF RELEASE OF PROTEIN BY LIPOLYTIC HORMONES AND INSULIN Journal of Biological Chemistry. ,vol. 241, pp. 3909- 3917 ,(1966) , 10.1016/S0021-9258(18)99793-0
A. Fortuño, A. Rodríguez, J. Gómez-Ambrosi, G. Frühbeck, J. Díez, Adipose tissue as an endocrine organ: role of leptin and adiponectin in the pathogenesis of cardiovascular diseases. Journal of Physiology and Biochemistry. ,vol. 59, pp. 51- 60 ,(2003) , 10.1007/BF03179868
Margit Pavelka, Roth, J. (Jürgen), Prof. Dr. Dr, Functional Ultrastructure: Atlas of Tissue Biology and Pathology ,(2011)
Michael W. Schwartz, Stephen C. Woods, Daniel Porte, Randy J. Seeley, Denis G. Baskin, Central nervous system control of food intake Nature. ,vol. 404, pp. 661- 671 ,(2000) , 10.1038/35007534
Joseph M. Rutkowski, Kathryn E. Davis, Philipp E. Scherer, Mechanisms of obesity and related pathologies: The macro- and microcirculation of adipose tissue FEBS Journal. ,vol. 276, pp. 5738- 5746 ,(2009) , 10.1111/J.1742-4658.2009.07303.X
A.S. Greenberg, J.J. Egan, S.A. Wek, N.B. Garty, E.J. Blanchette-Mackie, C. Londos, Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets. Journal of Biological Chemistry. ,vol. 266, pp. 11341- 11346 ,(1991) , 10.1016/S0021-9258(18)99168-4
Jose Ma Serra-Renom, Fat Grafting in Breast Reconstruction with Expanders and Prostheses in Patients Who Have Received Radiotherapy InTech. ,(2013) , 10.5772/56073