Pharmacogenetics, Pharmacogenomics, and Individualized Medicine

作者: Qiang Ma , Anthony Y. H. Lu

DOI: 10.1124/PR.110.003533

关键词:

摘要: Individual variability in drug efficacy and drug safety is a major challenge in current clinical practice, drug development, and drug regulation. For more than 5 decades, studies of …

参考文章(113)
Dominick J. Angiolillo, Antonio Fernandez-Ortiz, Esther Bernardo, Fernando Alfonso, Carlos Macaya, Theodore A. Bass, Marco A. Costa, Variability in Individual Responsiveness to Clopidogrel: Clinical Implications, Management, and Future Perspectives Journal of the American College of Cardiology. ,vol. 49, pp. 1505- 1516 ,(2007) , 10.1016/J.JACC.2006.11.044
R G Bell, Metabolism of vitamin K and prothrombin synthesis: anticoagulants and the vitamin K--epoxide cycle. Federation proceedings. ,vol. 37, pp. 2599- 2604 ,(1978)
J Green, E Banks, A Berrington, S Darby, H Deo, R Newton, N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interaction. British Journal of Cancer. ,vol. 83, pp. 412- 417 ,(2000) , 10.1054/BJOC.2000.1265
Toshiyuki Sakaeda, Tsutomu Nakamura, Masanori Horinouchi, Mikio Kakumoto, Nobuko Ohmoto, Toshiyuki Sakai, Yoshinori Morita, Takao Tamura, Nobuo Aoyama, Midori Hirai, Masato Kasuga, Katsuhiko Okumura, MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects. Pharmaceutical Research. ,vol. 18, pp. 1400- 1404 ,(2001) , 10.1023/A:1012244520615
TE Klein, RB Altman, Niclas Eriksson, BF Gage, SE Kimmel, MT Lee, NA Limdi, D Page, DM Roden, MJ Wagner, MD Caldwell, JA Johnson, YT Chen, MS Wen, Y Caraco, I Achache, S Blotnick, M Muszkat, JG Shin, HS Kim, G Suarez-Kurtz, JA Perini, E Silva-Assuncao, JL Anderson, BD Horne, JF Carlquist, RL Berg, JK Burmester, BC Goh, SC Lee, F Kamali, E Sconce, AK Daly, AH Wu, TY Langaee, H Feng, L Cavallari, K Momary, M Pirmohamed, A Jorgensen, CH Toh, P Williamson, H McLeod, JP Evans, KE Weck, C Brensinger, Y Nakamura, T Mushiroda, D Veenstra, L Meckley, MJ Rieder, AE Rettie, M Wadelius, H Melhus, CM Stein, U Schwartz, D Kurnik, E Deych, P Lenzini, C Eby, LY Chen, P Deloukas, A Motsinger-Reif, H Sagreiya, BS Srinivasan, E Lantz, T Chang, M Ritchie, LS Lu, Estimation of the warfarin dose with clinical and pharmacogenetic data The New England Journal of Medicine. ,vol. 360, pp. 753- 764 ,(2009) , 10.1056/NEJMOA0809329
Li-wei Liu, LIU Hong, Guo-Liang Chen, Yi-ling Huang, Lu-lu Han, Zhi-min Xu, Xiong-jing Jiang, Yi-shi Li, None, Angiotensin-converting enzyme gene I/D genotype affected metoprolol-induced reduction in 24-hour average heart rate. Chinese Medical Journal. ,vol. 123, pp. 1382- 1386 ,(2010)
Céline Verstuyft, Mathias Schwab, Elke Schaeffeler, Reinhold Kerb, Ulrich Brinkmann, Patrice Jaillon, Christian Funck-Brentano, Laurent Becquemont, Digoxin pharmacokinetics and MDR1 genetic polymorphisms European Journal of Clinical Pharmacology. ,vol. 58, pp. 809- 812 ,(2003) , 10.1007/S00228-003-0567-5