Génétique moléculaire des cancers : dualité hôte-tumeur

作者: J. Robert

DOI: 10.1007/978-2-8178-0445-3_1

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摘要: Depuis que les outils de la biologie moleculaire et du sequencage ont ete accessibles pour l’identification biomarqueurs, biologistes pathologistes se sont focalises sur le genome tumoral, dont alterations responsables l’oncogenese progression des cancers, laissant aux epidemiologistes l’etude constitutionnel facteurs risque survenue cancers. L’oncologie offre en effet cette particularite d’offrir deux genomes distincts a chercheurs : patient celui tumeur qui, certes, derive premier mais apres avoir subi alterations, d’importance tres variable.

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