摘要: MicroRNA (miRNA ) alterations are involved in the initiation and progression of human cancer. The causes widespread differential expression miRNA genes malignant compared with normal cells can be explained by location these cancer-associated genomic regions, epigenetic mechanisms processing machinery. MiRNA-expression profiling tumours has identified signatures associated diagnosis, staging, progression, prognosis response to treatment. In addition, been exploited identify that might represent downstream targets activated oncogenic pathways, or target protein- coding
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