Low immunogenicity of allogeneic human umbilical cord blood-derived mesenchymal stem cells in vitro and in vivo.

作者: Miyoung Lee , Sang Young Jeong , Jueun Ha , Miyeon Kim , Hye Jin Jin

DOI: 10.1016/J.BBRC.2014.03.051

关键词:

摘要: … the immunogenicity of human mesenchymal stem cells (MSCs… that allogeneic human umbilical cord blood derived-MSCs (… isolated hUCB-derived CD34+ cells intravenously into …

参考文章(30)
Sang Young Jeong, Dong Hyun Kim, Jueun Ha, Hye Jin Jin, Soon-Jae Kwon, Jong Wook Chang, Soo Jin Choi, Wonil Oh, Yoon Sun Yang, Gonhyung Kim, Jae Sung Kim, Jung-Ro Yoon, Dong Hyung Cho, Hong Bae Jeon, Thrombospondin‐2 secreted by human umbilical cord blood‐derived mesenchymal stem cells promotes chondrogenic differentiation Stem Cells. ,vol. 31, pp. 2136- 2148 ,(2013) , 10.1002/STEM.1471
L. M. Tobin, M. E. Healy, K. English, B. P. Mahon, Human mesenchymal stem cells suppress donor CD4(+) T cell proliferation and reduce pathology in a humanized mouse model of acute graft-versus-host disease. Clinical and Experimental Immunology. ,vol. 172, pp. 333- 348 ,(2013) , 10.1111/CEI.12056
Todd Pearson, Dale L. Greiner, Leonard D. Shultz, Creation of “Humanized” Mice to Study Human Immunity Current protocols in immunology. ,vol. 81, ,(2008) , 10.1002/0471142735.IM1521S81
Giselle Chamberlain, James Fox, Brian Ashton, Jim Middleton, Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells. ,vol. 25, pp. 2739- 2749 ,(2007) , 10.1634/STEMCELLS.2007-0197
Alain J. Poncelet, Jonathan Vercruysse, Alain Saliez, Pierre Gianello, Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo. Transplantation. ,vol. 83, pp. 783- 790 ,(2007) , 10.1097/01.TP.0000258649.23081.A3
Leonard D. Shultz, Fumihiko Ishikawa, Dale L. Greiner, Humanized mice in translational biomedical research Nature Reviews Immunology. ,vol. 7, pp. 118- 130 ,(2007) , 10.1038/NRI2017
Fumihiko Ishikawa, Masaki Yasukawa, Bonnie Lyons, Shuro Yoshida, Toshihiro Miyamoto, Goichi Yoshimoto, Takeshi Watanabe, Koichi Akashi, Leonard D. Shultz, Mine Harada, Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice Blood. ,vol. 106, pp. 1565- 1573 ,(2005) , 10.1182/BLOOD-2005-02-0516
Sabine Schu, Mikhail Nosov, Lisa O'Flynn, Georgina Shaw, Oliver Treacy, Frank Barry, Mary Murphy, Timothy O'Brien, Thomas Ritter, Immunogenicity of allogeneic mesenchymal stem cells. Journal of Cellular and Molecular Medicine. ,vol. 16, pp. 2094- 2103 ,(2012) , 10.1111/J.1582-4934.2011.01509.X
Manoj M. Lalu, Lauralyn McIntyre, Christina Pugliese, Dean Fergusson, Brent W. Winston, John C. Marshall, John Granton, Duncan J. Stewart, , Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials PLoS ONE. ,vol. 7, pp. e47559- ,(2012) , 10.1371/JOURNAL.PONE.0047559