Optimization of patient selection for EGFR-TKIs in advanced non-small cell lung cancer by combined analysis of KRAS , PIK3CA , MET, and non-sensitizing EGFR mutations

Stephen L. Graziano, Gary P. Gamble, Nancy B. Newman, Lynn Z. Abbott, Michelle Rooney, Sulagna Mookherjee, Melissa L. Lamb, Leslie J. Kohman, Bernard J. Poiesz, Prognostic Significance of K-ras Codon 12 Mutations in Patients With Resected Stage I and II Non–Small-Cell Lung Cancer Journal of Clinical Oncology. ,vol. 17, pp. 668- 668 ,(1999) , 10.1200/JCO.1999.17.2.668

Sreenath V. Sharma, Daphne W. Bell, Jeffrey Settleman, Daniel A. Haber, Epidermal growth factor receptor mutations in lung cancer Nature Reviews Cancer. ,vol. 7, pp. 169- 181 ,(2007) , 10.1038/NRC2088

James R. Jett, State of the Journal: 2011 Journal of Thoracic Oncology. ,vol. 6, pp. 1- ,(2011) , 10.1097/JTO.0B013E3182068E8B

Elaine H. Lim, Shen-Li Zhang, Jia-Liang Li, Wee-See Yap, Tse-Chiang Howe, Bien-Peng Tan, Yong-Shyan Lee, Daniel Wong, Kay-Leong Khoo, Kar-Yin Seto, Lenny Tan, Thirugananam Agasthian, Heng-Nung Koong, John Tam, Christie Tan, Michael Caleb, Alex Chang, Alan Ng, Patrick Tan, Using Whole Genome Amplification (WGA) of Low-Volume Biopsies to Assess the Prognostic Role of EGFR, KRAS, p53, and CMET Mutations in Advanced-Stage Non-small Cell Lung Cancer (NSCLC) Journal of Thoracic Oncology. ,vol. 4, pp. 12- 21 ,(2009) , 10.1097/JTO.0B013E3181913E28

Joan H. Schiller, David Harrington, Chandra P. Belani, Corey Langer, Alan Sandler, James Krook, Junming Zhu, David H. Johnson, Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. The New England Journal of Medicine. ,vol. 346, pp. 92- 98 ,(2002) , 10.1056/NEJMOA011954

Heidi Greulich, Tzu-Hsiu Chen, Whei Feng, Pasi A Jänne, James V Alvarez, Mauro Zappaterra, Sara E Bulmer, David A Frank, William C Hahn, William R Sellers, Matthew Meyerson, Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants PLoS Medicine. ,vol. 2, pp. e313- ,(2005) , 10.1371/JOURNAL.PMED.0020313

John Mendelsohn, Jose Baselga, Status of Epidermal Growth Factor Receptor Antagonists in the Biology and Treatment of Cancer Journal of Clinical Oncology. ,vol. 21, pp. 2787- 2799 ,(2003) , 10.1200/JCO.2003.01.504

Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella, Sarada Gurubhagavatula, Ross A. Okimoto, Brian W. Brannigan, Patricia L. Harris, Sara M. Haserlat, Jeffrey G. Supko, Frank G. Haluska, David N. Louis, David C. Christiani, Jeff Settleman, Daniel A. Haber, Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib The New England Journal of Medicine. ,vol. 350, pp. 2129- 2139 ,(2004) , 10.1056/NEJMOA040938

Hee Joung Kim, Kye Young Lee, Young-Chul Kim, Kyu-Sik Kim, Sung Yong Lee, Tae Won Jang, Min Ki Lee, Kyeong-Cheol Shin, Gwan Ho Lee, Jae Chol Lee, Jeong Eun Lee, Sun Young Kim, Detection and comparison of peptide nucleic acid-mediated real-time polymerase chain reaction clamping and direct gene sequencing for epidermal growth factor receptor mutations in patients with non-small cell lung cancer. Lung Cancer. ,vol. 75, pp. 321- 325 ,(2012) , 10.1016/J.LUNGCAN.2011.08.005

Román Pérez-Soler, Abraham Chachoua, Lisa A. Hammond, Eric K. Rowinsky, Mark Huberman, Daniel Karp, James Rigas, Gary M. Clark, Pedro Santabárbara, Philip Bonomi, Determinants of Tumor Response and Survival With Erlotinib in Patients With Non—Small-Cell Lung Cancer Journal of Clinical Oncology. ,vol. 22, pp. 3238- 3247 ,(2004) , 10.1200/JCO.2004.11.057