Status of Epidermal Growth Factor Receptor Antagonists in the Biology and Treatment of Cancer

作者: John Mendelsohn , Jose Baselga

DOI: 10.1200/JCO.2003.01.504

关键词: Tropomyosin receptor kinase CCancer researchROR1Growth factor receptorEpidermal growth factor receptorInsulin-like growth factor 1 receptorMedicineReceptor tyrosine kinaseERBB3Tyrosine kinase

摘要: The epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor of the ErbB family that is abnormally activated in many epithelial tumors. Receptor activation leads to …

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