Fluorescein Sodium-Guided Surgery of Malignant Brain Tumors: History, Current Concepts, and Future Project.
作者： Karl-michael Schebesch , Alexander Brawanski , Christoph Hohenberger , Julius Hohne
DOI: 10.5137/1019-5149.JTN.16952-16.0
关键词:
摘要: Fluorescein sodium (FL)-guided resection has become an important and beneficial treatment method for malignant brain tumors. FL-guided improves the rate of gross total in high-grade gliomas (HGG) cerebral metastases (CM). FL sensitively visualizes disruption blood-brain barrier area surrounding lesions, similar to contrast-enhanced T1-weighted MR sequences. This review current literature summarizes history neurosurgery from 1946 until today. We discuss molecular mechanism accumulation tumors provide overview practice using applying a dedicated surgical microscope filter. Additionally, we outline ongoing trials future projects.
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