作者: Sarah Tomkovich , Christian Jobin
DOI: 10.1038/S41416-018-0101-2
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摘要: A recent study by Dejea et al. has demonstrated that two enterotoxigenic bacteria frequently associated with sporadic colorectal cancer, Bacteroides fragilis and pks+ Escherichia coli, are found together in biofilms on tissue from patients familial adenomatous polyposis. In preclinical mouse models, these their corresponding toxins work synergistically to promote colon cancer.