Congenitally Corrected Transposition of the Great Arteries

摘要: Objectives The objective was to evaluate the systemic ventricular ejection fraction (SVEF) at time of atrioventricular valve (SAVV) replacement as a predictor SVEF ≥1 year after surgery in patients with congenitally corrected transposition great arteries (CCTGA). Background Progressive SAVV regurgitation causes failure CCTGA patients, who are commonly referred late for intervention. Survival is poor when pre-operative l44%. Methods We retrospectively reviewed 46 (pre-operative ≥40% 27 and l40% 19 patients) 2 good-sized ventricles, morphologically right ventricle, requiring surgery. Median follow-up not different (8.8 years) or (7.7 years, p = 0.36). Results Pre-operative only independent ≥1-year post-operative (p l 0.0001). preserved (defined ≥40%) 63% underwent an compared 10.5% l40%. variables associated mortality were ≤40%, subpulmonary systolic pressure ≥50 mm Hg, atrial fibrillation, New York Heart Association functional class III IV. Conclusions Post-operative function can be predicted from SVEF. For best results, operation should considered earlier stage, before falls below 40% rises above 50 Hg.