作者: Peter Bentzer , James A. Russell , Keith R. Walley
DOI: 10.1016/J.CCM.2015.05.009
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摘要: Recent research has identified promising targets for therapeutic interventions aimed at modulating the inflammatory response in sepsis. Herein, authors describe mechanisms involved clearance of pathogen toxin from circulation and potential enhancing mechanisms. The also advances understanding innate immune as targets. Finally, novel treatment strategies decreasing vascular leak are discussed.