作者: Edward S. Fonda , John R. Diehl , C.Richard Bard , Terry E. Riser , Robert R. Kraeling
DOI: 10.1016/0090-6980(81)90162-3
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摘要: The effect of prostaglandin F2 alpha (PGF2 alpha) on serum luteinizing hormone (LH), testosterone (T), prolactin (PRL) and cortisol (CS) was studied in the boar. Indwelling cannulae were placed nonsurgically jugular vein six 8 to 9 month-old boars weighing 130 160 kilograms. Twenty-four hr after cannulation, blood samples collected every 30 min from 0630 1830 hours. Immediately second sample (0700 hr) three injected intramuscularly (IM) with 20 mg PGF2 IM saline (C). Serum concentrations LH, T, PRL CS quantitated by radioimmunoassay. LH T similar for C throughout sampling period. In contrast, increased basal (mean +/- SE) 2.1 .1 ng/ml 24.0 .9 11.6 .3 86.9 9.8 ng/ml, respectively, within injections then decreased control levels over next 2.0 2.5