Progressive postnatal dilation of brain ventricles in spontaneously hypertensive rats.
作者： Sue Ritter , Thu T. Dinh
DOI: 10.1016/0006-8993(86)90488-9
关键词:
摘要: Cross-sectional areas of the forebrain ventricles were measured from coronal sections in spontaneously hypertensive rats (SHRs) 4, 8, 12, 16, 21 and 56 weeks age age-matched Wistar--Kyoto (WKY) Sprague--Dawley (SD) normotensive rats. Progressive ventricular dilation associated attrition brain tissue was observed SHRs both sexes after 4 age, present animals obtained two different suppliers. In some SHRs, ventricle size increased to 270% control. Hence, it seems likely that systemic behavioral signs which are concomitant with hypertension SHR may be attributable hydrocephalus its neuropathological correlates.
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