Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
作者： Hans E. Purkey , Kirk Robarge , Jinhua Chen , Zhongguo Chen , Laura B. Corson
DOI: 10.1021/ACSMEDCHEMLETT.6B00190
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摘要: … LDHA inhibition for the treatment of cancer. A recent report from our laboratories identified the lactate dehydrogenase … breast cancer tumors. (9) Given this linkage, we sought a pan-LDH …
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