THE TREATMENT OF THYROTOXICOSIS WITH AMINOTHIAZOLE—RESULTS IN TWENTY-THREE CASES

作者: JEANNETTE S. McCONNELL , JOHN W. FROST , ROBERT W. WILBUR , EDWARD ROSE

DOI: 10.1210/JCEM-7-12-812

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摘要: IT is our purpose in this report to present the results of treatment with aminothiazole 23 cases thyrotoxicosis. This compound (Fig. 1) appears have been first used clinically thyrotoxicosis France 1943 (9), following observation goitrogenesis and improvement thyrotoxic symptoms among workers chemical plants who were exposed compound. Perrault Bovet (10) other French writers (3, 4, 6) reported satisfactory from use thyrotoxicosis, but their data are not susceptible critical analysis. The only its clinical which we found American literature that Williams (11), employed it 9 cases. One patient developed jaundice another dermatitis, fever arthritis while under treatment. lists as low potency desirability antithyroid drugs. goitrogenic action rat was by Astwood oth...

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E. B. ASTWOOD, A BISSELL, A. M. HUGHES, FURTHER STUDIES ON THE CHEMICAL NATURE OF COMPOUNDS WHICH INHIBIT THE FUNCTION OF THE THYROID GLAND11 Endocrinology. ,vol. 37, pp. 456- 481 ,(1945) , 10.1210/ENDO-37-6-456
Marcel Perrault, Daniel Bovet, Aminothiazole in the treatment of thyrotoxicosis. The Lancet. ,vol. 247, pp. 731- 734 ,(1946) , 10.1016/S0140-6736(46)90529-6
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