ANTITHYROID DRUGS: III

作者: ROBERT H. WILLIAMS

DOI: 10.1001/ARCHINTE.1947.00220130019002

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摘要: THE OBSCURITY of the fundamental disturbances in body leading to development thyrotoxicosis has interfered with a direct approach therapy this disease. Although much progress been made controlling it by surgical measures, great deal is left be desired, both as concerns principles and results treatment. The ideal one which simple, inexpensive, available everyone, does not necessitate hospitalization, associated significant toxic reactions permit invalidism. These ideals do seem reasonable an expectation treatment chemotherapy or physical therapy, but they must developed greater extent. Recent contributions1to physiology thyroid have led clearer understanding some problems thyrotoxicosis. PHYSIOLOGIC-CHEMICAL CONSIDERATIONS OF THYROID FUNCTION Whereas complete proof substantiate

参考文章(23)
Some new approaches to the physiology of the thyroid. Annals of Internal Medicine. ,vol. 19, pp. 567- 586 ,(1943) , 10.7326/0003-4819-19-4-567
G. S. CARTER, F. G. MANN, J. HARLEY-MASON, G. N. JENKINS, Paraxanthine as a Natural Antithyroid Substance Nature. ,vol. 151, pp. 728- 730 ,(1943) , 10.1038/151728C0
Robert H. Williams, Antithyroid Drugs: I. Tetramethylthiourea and Diethylthiourea1 The Journal of Clinical Endocrinology and Metabolism. ,vol. 5, pp. 210- 216 ,(1945) , 10.1210/JCEM-5-5-210
Rulon W. Rawson, Francis D. Moore, Wendell Peacock, J. H. Means, Oliver Cope, Charlotte B. Riddell, EFFECT OF IODINE ON THE THYROID GLAND IN GRAVES' DISEASE WHEN GIVEN IN CONJUNCTION WITH THIOURACIL-A TWO-ACTION THEORY OF IODINE. Journal of Clinical Investigation. ,vol. 24, pp. 869- 877 ,(1945) , 10.1172/JCI101674
A. R. MARTIN, F. L. ROSE, G. SWAIN, Anti-sulphanilamide Activity of 2-Aminopyrimidine-5-carboxylic Acid Nature. ,vol. 154, pp. 639- 639 ,(1944) , 10.1038/154639B0
Wilbur H. Miller, Richard O. Roblin, E. B. Astwood, Studies in Chemotherapy. XI. Oxidation of 2-Thiouracil and Related Compounds by Iodine Journal of the American Chemical Society. ,vol. 67, pp. 2201- 2204 ,(1945) , 10.1021/JA01228A043
J. H. M Means, The thyroid and its diseases ,(1975)
S. Hertz, A. Roberts, R. D. Evans, Radioactive Iodine as an Indicator in the Study of Thyroid Physiology. Experimental Biology and Medicine. ,vol. 38, pp. 510- 513 ,(1938) , 10.3181/00379727-38-9915P