Nucleated red cell function: metabolism and pH regulation
作者： Robert G. Boutilier , Ralph A. Ferguson
DOI: 10.1139/Z89-421
关键词:
摘要: The full extent and apportionment of aerobic anaerobic contributions to energy transduction for membrane pumps associated with cellular pH regulation are very poorly understood. One way approaching this problem at the level is by using nucleated erythrocyte as a model cell. Indeed, capacity salmonid erythrocytes their β-adrenergic mediated offers "pH regulating system" examining strategies response acute (or) chronic changes in oxygen availability. Much our work has focused on balance between metabolic production maintenance erythrocytic through primarily or secondarily active ionic exchange mechanisms cell membrane. Upon adrenergic stimulation, rise cyclic AMP activates Na+–H+ exchanger, leading alkalinization an elevation intracellular Na+. increased Na+ evidently stimulates Na+,K+-ATPase activity ATP consumption matched wit...
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