18F-FLT PET for Visualization of Laryngeal Cancer: Comparison with 18F-FDG PET
作者： Albert J H Suurmeijer , Harald J Hoekstra , David C P Cobben , Bram Maas , Pieter L Jager
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摘要: The feasibility of F-18-3'-fluoro-3'-deoxy-L-thymidine PET (FLT PET) for detecting laryngeal cancer was investigated and compared with F-18-FDG PET. Methods: Eleven patients diagnosed or strongly suspected having recurrent 10 histologically proven primary underwent attenuation-corrected F-18-FLT imaging 60 min after injection a median 213 MBq (range, 175-400 MBq) 90 340 165-650 F-18-FDG. All were staged by endoscopy CT according to the Union Internationale Contre la Cancer TNM staging system. biopsy area imaging. Lesions seen on histopathologic results. Mean SUVs, maximum tumor-to-nontumor (TNT) ratios calculated Wilcoxon nonparametric testing used comparison uptake. Spearman correlation coefficient correlate mean TNT Two-tailed P values
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