Prognostic factors of hepatectomy in initially unresectable colorectal liver metastasis: Indication for conversion therapy

摘要: The aim of the present study was to retrospectively identify prognostic factors for long-term cumulative survival following liver resection in patients with primarily unresectable colorectal cancer who had previously received conversion therapy. A multicentre designed ascertain appropriate indication included 34 underwent therapy at 5 university hospitals. Patients' background, operative factors, recurrence rate and were evaluated, influencing outcomes identified. median duration preoperative chemotherapy 3 months response 39.8%. Upon resection, tumour size 47 mm number tumours 4. recurrence-free rates years after 13.7 39.3%, respectively. Postoperative complications developed 12 patients. >40% indicated regards assessed an absence postoperative noted. It revealed that should be considered prior particularly exceeding 40%. Absence is also independent predictor resection. In light these findings, it consisted optimal could used as indicator surgical addition, meticulous intra- managements are important decreasing improving survival.