Intraoperative Hemoglobin Levels and Transfusion Independently Predict Stroke After Cardiac Operations

摘要: Background Anemia has been associated with adverse cerebrovascular outcomes, particularly after cardiac operations. This study was conducted to determine if hemoglobin levels during and cardiopulmonary bypass (CPB) predict postoperative stroke in surgical patients, independent of transfusion requirements. Methods Individuals who had sustained a clinical (cases) were matched 1:2 controls by age, sex, procedure, year operation. In 617 conditional logistic regression performed analyze associations between before CPB, stroke. Results After adjustment for potentially confounding vascular risk factors, lower CPB higher stroke, even the amount packed red blood cells transfused (adjusted odds ratio, 1.28; 95% confidence interval, 1.00 1.64, per point level; adjusted ratio quartile this model, 1.37; 1.02 1.83). Similar not found concentrations preoperatively nor change from CPB. A post-CPB level below median 37% increased occurring (p = 0.02). Conclusions Lower intraoperative requirements are each independently Reduced cerebral oxygen delivery due anemia may contribute injury coronary artery grafting.