Use of Blood Products and Diseased Ascending Aorta Are Determinants of Stroke After Off-Pump Coronary Artery Bypass Grafting.

摘要: Objective To examine the effect of blood products on occurrence stroke after coronary artery surgery. Design Institutional retrospective analysis. Setting University hospital. Participants One thousand three hundred fourteen patients undergoing Interventions Off-pump bypass grafting (OPCAB). Epiaortic ultrasound was performed in all patients. Measurements and Main Results Complete pre-, intra- postoperative data including number transfused as well timing, type, course were available Postoperative occurred 23 (1.8%). Logistic regression identified transfusion platelets (3.6% v 1.1%, p = 0.003, OR 3.34, 95%CI 1.46-7.67) diseased ascending aorta (3.0% 1.2%, 0.022, 2.64, 95% CI 1.15-6.06) independent predictors stroke. When these variables adjusted for CHA2DS2VASc (p 0.005, 1.44, 1.12-1.86), only 0.012, 2.91, 1.26-6.70) associated with Neither nadir hematocrit day surgery nor during perioperative period an predictor Chi-squared automatic interaction detection analysis solvent/detergent-treated plasma (Octaplas; Octapharma AG, Lachen, Switzerland) units>2 platelet units>4 along The rate 8.9% receiving>2 units Octaplas having a aorta. In receiving≤2 Octaplas, high 3.8% receiving>4 platelets. Conclusions results this study indicated that atherosclerosis and/or OPCAB.