PIK3CA Gene Alterations in Human Cancers

作者: Sérgia Velho , Carla Oliveira , Raquel Seruca

DOI: 10.1007/978-1-59745-576-3_10

关键词:

摘要: Mutations or amplification of the chromosomal region containing PIK3CA gene, coding for p110α catalytic subunit class IA PI3K, were described in diverse tumor models. In this review, we will focus on localization and type mutations their association with signaling pathways cellular effects different types.

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