DABCO-catalyzed consecutive one pot four-component protocol for the synthesis of a novel class of (Z)-5-(3-hydroxy-2-oxoindolin-3-yl)-2-iminothiazolidin-4-ones

作者: Madhu Babu Bejjam , G. Santhosh Kumar , A. Swetha , H. M. Meshram

DOI: 10.1039/C5RA24127H

关键词:

摘要: A DABCO catalyzed, novel and efficient one-pot, four component protocol has been developed for the synthesis of (Z)-5-(3-hydroxy-2-oxoindolin-3-yl)-2-iminothiazolidin-4-one scaffolds under metal-free conditions. By virtue simple readily available starting materials, mild reaction conditions, high bioactivity oxindole derivatives, this promises diverse applications in medical chemistry.

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